Second COVID-19 Vaccine Dose For 52 Year Old Man Linked To Aphasia According To 2021 Medical Journal Report

By Mary Fanning and Alan Jones | March 31, 2022

A 52 year-old man suffered from a sudden case of aphasia seven days after taking a second dose of an mRNA-based SARS-CoV-2 vaccine, according to a medical journal report published in late 2021.

According to the report, published in the December 2021 issue of the medical journal Brain Hemorrhages (Volume 2, Issue 4), also available from the National Institutes of Health (NIH) National Library of Medicine:

A 52yo male developed sudden-onset reading difficulty and aphasia 7d after the second dose of an mRNA-based SARS-CoV-2 vaccine. He had a previous history of myocardial infarction, arterial hypertension, hyperlipidemia, and nephrolithiasis. Blood pressure was slightly elevated on admission. Blood tests revealed mildly elevated D-dimer, pre-diabetes and hyperuricemia. Cerebral magnetic resonance imaging revealed an intracerebral bleeding (ICB) in the left temporal lobe. Aphasia resolved almost completely within a few days. Blood pressure values were normal throughout hospitalisation. Whether there was a causal relation between the ICB and the vaccination remains speculative but cannot be definitively excluded.


A second dose of a SARS-CoV-2 vaccination may be followed by ICB. Though the pathophysiology of ICB remains unexplained a causal relation between ICB and the vaccination cannot be excluded. Risk factors for ICB should be carefully monitored in patients undergoing SARS-CoV-2 vaccination.




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